产品名称: | Recombinant Saccharomyces cerevisiae NADPH-dependent methylglyoxal reductase GRE2 (GRE2), partial |
货号: | TSANTI000459 |
纯度: | Greater than 90% as determined by SDS-PAGE. |
生物活性: | Not Test |
基因名: | GRE2 |
Uniprot No.: | Q12068 |
别名: | (3-methylbutanal reductase)(Genes de respuesta a estres protein 2)(Isovaleraldehyde reductase) |
种属: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Bakers yeast) |
蛋白长度: | Partial |
来源: | E.coli |
分子量: | 28.6 |
表达区域: | 1-120aa |
氨基酸序列 | MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE |
蛋白标签: | N-terminal 6xHis-KSI-tagged |
产品提供形式: | Liquid or Lyophilized powder |
缓冲液: | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
复溶: | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
储存条件: | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
保质期: | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. |
货期: | Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
注意事项: | Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week. |
Datasheet & COA: | Please contact us to get it. |
功能: | Catalyzes the irreversible reduction of the cytotoxic compound methylglyoxal (MG, 2-oxopropanal) to (S)-lactaldehyde as an alternative to detoxification of MG by glyoxalase I GLO1. MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation. Also catalyzes the reduction of 3-methylbutanal to 3-methylbutanol. Acts as a suppressor of 3-methylbutanol-induced filamentation by modulating the levels of 3-methylbutanal, the signal to which cells respond by filamentation. Also involved in ergosterol metabolism. |
基因功能参考文献: | Gre2 forms a homodimer, each subunit of which contains an N-terminal Rossmann-fold domain and a variable C-terminal domain, which participates in substrate recognition. PMID: 24879127 |
亚细胞定位: | Cytoplasm. Nucleus. |
蛋白家族: | NAD(P)-dependent epimerase/dehydratase family, Dihydroflavonol-4-reductase subfamily |
数据库链接: | KEGG: sce:YOL151W |
浙江省宁波市镇海区庄市街道兴庄路9号
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产品名称: | Recombinant Saccharomyces cerevisiae NADPH-dependent methylglyoxal reductase GRE2 (GRE2), partial |
货号: | TSANTI000459 |
纯度: | Greater than 90% as determined by SDS-PAGE. |
生物活性: | Not Test |
基因名: | GRE2 |
Uniprot No.: | Q12068 |
别名: | (3-methylbutanal reductase)(Genes de respuesta a estres protein 2)(Isovaleraldehyde reductase) |
种属: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Bakers yeast) |
蛋白长度: | Partial |
来源: | E.coli |
分子量: | 28.6 |
表达区域: | 1-120aa |
氨基酸序列 | MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE |
蛋白标签: | N-terminal 6xHis-KSI-tagged |
产品提供形式: | Liquid or Lyophilized powder |
缓冲液: | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
复溶: | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
储存条件: | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
保质期: | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. |
货期: | Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
注意事项: | Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week. |
Datasheet & COA: | Please contact us to get it. |
功能: | Catalyzes the irreversible reduction of the cytotoxic compound methylglyoxal (MG, 2-oxopropanal) to (S)-lactaldehyde as an alternative to detoxification of MG by glyoxalase I GLO1. MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation. Also catalyzes the reduction of 3-methylbutanal to 3-methylbutanol. Acts as a suppressor of 3-methylbutanol-induced filamentation by modulating the levels of 3-methylbutanal, the signal to which cells respond by filamentation. Also involved in ergosterol metabolism. |
基因功能参考文献: | Gre2 forms a homodimer, each subunit of which contains an N-terminal Rossmann-fold domain and a variable C-terminal domain, which participates in substrate recognition. PMID: 24879127 |
亚细胞定位: | Cytoplasm. Nucleus. |
蛋白家族: | NAD(P)-dependent epimerase/dehydratase family, Dihydroflavonol-4-reductase subfamily |
数据库链接: | KEGG: sce:YOL151W |