Recombinant Helicobacter pylori DNA protection during starvation protein (dps)
Recombinant Helicobacter pylori DNA protection during starvation protein (dps)
规格:
货期:
编号:TSANTI000492
品牌:Testobio
| 产品名称: | Recombinant Helicobacter pylori DNA protection during starvation protein (dps) |
| 货号: | TSANTI000492 |
| 纯度： | Greater than 90% as determined by SDS-PAGE. |
| 基因名： | dps |
| Uniprot No.： | P43313 |
| 别名： | dps; napA; HP_0243DNA protection during starvation protein; EC 1.16.-.-; Bacterioferritin; HP-NAP; Neutrophil-activating protein A; NAP A |
| 种属： | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
| 蛋白长度： | Full Length |
| 来源： | E.coli |
| 分子量： | 32.9kDa |
| 表达区域： | 1-144aa |
| 氨基酸序列 | MKTFEILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIVQLGHHPLVTLSEAIKLTRVKEETKTSFHSKDIFKEILEDYKYLEKEFKELSNTAEKEGDKVTVTYADDQLAKLQKSIWMLQAHLA |
| 蛋白标签： | N-terminal 6xHis-SUMO-tagged |
| 产品提供形式： | Liquid or Lyophilized powder |
| 缓冲液： | Tris-based buffer,50% glycerol |
| 储存条件： | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| 保质期： | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. |
| 货期： | 3-7 business days |
| 注意事项： | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Datasheet & COA： | Please contact us to get it. |
| 功能： | Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases. |
| 基因功能参考文献： | H. pylori NapA has unique and separate roles in gastric pathogenesis. PMID: 17030577 |
| 亚细胞定位： | Cytoplasm. |
| 蛋白家族： | Dps family |
| 数据库链接： | KEGG: heo:C694_01230 |
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Recombinant Helicobacter pylori DNA protection during starvation protein (dps)
Recombinant Helicobacter pylori DNA protection during starvation protein (dps)
规格:
货期:
编号:TSANTI000492
品牌:Testobio
| 产品名称: | Recombinant Helicobacter pylori DNA protection during starvation protein (dps) |
| 货号: | TSANTI000492 |
| 纯度： | Greater than 90% as determined by SDS-PAGE. |
| 基因名： | dps |
| Uniprot No.： | P43313 |
| 别名： | dps; napA; HP_0243DNA protection during starvation protein; EC 1.16.-.-; Bacterioferritin; HP-NAP; Neutrophil-activating protein A; NAP A |
| 种属： | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
| 蛋白长度： | Full Length |
| 来源： | E.coli |
| 分子量： | 32.9kDa |
| 表达区域： | 1-144aa |
| 氨基酸序列 | MKTFEILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIVQLGHHPLVTLSEAIKLTRVKEETKTSFHSKDIFKEILEDYKYLEKEFKELSNTAEKEGDKVTVTYADDQLAKLQKSIWMLQAHLA |
| 蛋白标签： | N-terminal 6xHis-SUMO-tagged |
| 产品提供形式： | Liquid or Lyophilized powder |
| 缓冲液： | Tris-based buffer,50% glycerol |
| 储存条件： | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| 保质期： | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. |
| 货期： | 3-7 business days |
| 注意事项： | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Datasheet & COA： | Please contact us to get it. |
| 功能： | Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases. |
| 基因功能参考文献： | H. pylori NapA has unique and separate roles in gastric pathogenesis. PMID: 17030577 |
| 亚细胞定位： | Cytoplasm. |
| 蛋白家族： | Dps family |
| 数据库链接： | KEGG: heo:C694_01230 |