产品名称: | Recombinant Saccharomyces cerevisiae Eukaryotic translation initiation factor 5A-1 (HYP2) |
货号: | TSANTI000594 |
纯度: | Greater than 90% as determined by SDS-PAGE. |
基因名: | HYP2 |
Uniprot No.: | P23301 |
别名: | HYP2; TIF51A; YEL034W; SYGP-ORF21Eukaryotic translation initiation factor 5A-1; eIF-5A-1; Hypusine-containing protein HP2; eIF-4D |
种属: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Bakers yeast) |
蛋白长度: | Full Length of Mature Protein |
来源: | E.coli |
分子量: | 33.0kDa |
表达区域: | 2-157aa |
氨基酸序列 | SDEEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDGFLSLMNMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEAARTD |
蛋白标签: | N-terminal 6xHis-SUMO-tagged |
产品提供形式: | Liquid or Lyophilized powder |
缓冲液: | Tris-based buffer,50% glycerol |
储存条件: | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
保质期: | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. |
货期: | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
注意事项: | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Datasheet & COA: | Please contact us to get it. |
功能: | mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Essential for polarized growth, a process necessary for G1/S transition. May mediate large range of effects of the polyamine spermidine in the cell. |
基因功能参考文献: | the ability of eIF5A from tif51A-4 to bind to the ribosome while potentially blocking physical interaction with P-tRNA could explain its dominant negative phenotype. PMID: 27388480 |
亚细胞定位: | Cytoplasm. Note=Concentrates in the perinuclear region. |
蛋白家族: | EIF-5A family |
数据库链接: | KEGG: sce:YEL034W |
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产品名称: | Recombinant Saccharomyces cerevisiae Eukaryotic translation initiation factor 5A-1 (HYP2) |
货号: | TSANTI000594 |
纯度: | Greater than 90% as determined by SDS-PAGE. |
基因名: | HYP2 |
Uniprot No.: | P23301 |
别名: | HYP2; TIF51A; YEL034W; SYGP-ORF21Eukaryotic translation initiation factor 5A-1; eIF-5A-1; Hypusine-containing protein HP2; eIF-4D |
种属: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Bakers yeast) |
蛋白长度: | Full Length of Mature Protein |
来源: | E.coli |
分子量: | 33.0kDa |
表达区域: | 2-157aa |
氨基酸序列 | SDEEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDGFLSLMNMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEAARTD |
蛋白标签: | N-terminal 6xHis-SUMO-tagged |
产品提供形式: | Liquid or Lyophilized powder |
缓冲液: | Tris-based buffer,50% glycerol |
储存条件: | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
保质期: | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. |
货期: | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
注意事项: | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Datasheet & COA: | Please contact us to get it. |
功能: | mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Essential for polarized growth, a process necessary for G1/S transition. May mediate large range of effects of the polyamine spermidine in the cell. |
基因功能参考文献: | the ability of eIF5A from tif51A-4 to bind to the ribosome while potentially blocking physical interaction with P-tRNA could explain its dominant negative phenotype. PMID: 27388480 |
亚细胞定位: | Cytoplasm. Note=Concentrates in the perinuclear region. |
蛋白家族: | EIF-5A family |
数据库链接: | KEGG: sce:YEL034W |