产品名称: | Recombinant Candida albicans Hyphal wall protein 1 (HWP1), partial |
货号: | TSANTI000690 |
纯度: | Greater than 85% as determined by SDS-PAGE. |
基因名: | HWP1 |
Uniprot No.: | P46593 |
别名: | HWP1; ECE2; CAALFM_C403570WA; CaO19.1321; CaO19.8901; Hyphal wall protein 1; Cell elongation protein 2 |
种属: | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
蛋白长度: | Partial |
来源: | Yeast |
分子量: | 21.7 kDa |
表达区域: | 27-203aa |
氨基酸序列 | GQGETEEALIQKRSYDYYQEPCDDYPQQQQQQEPCDYPQQQQQEEPCDYPQQQPQEPCDYPQQPQEPCDYPQQPQEPCDYPQQPQEPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDQPDDNPPIPNIPTDWIPNIPTDWIPDIPEKPTTPATTPNIPA |
蛋白标签: | N-terminal 6xHis-tagged |
产品提供形式: | Liquid or Lyophilized powder |
缓冲液: | Tris-based buffer,50% glycerol |
储存条件: | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
保质期: | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. |
货期: | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
注意事项: | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Datasheet & COA: | Please contact us to get it. |
功能: | Major hyphal cell wall protein which plays a role of adhesin and is required for mating, normal hyphal development, cell-to-cell adhesive functions necessary for biofilm integrity, attachment to host, and virulence. Promotes interactions with host and bacterial molecules, thus leading to effective colonization within polymicrobial communities. Plays a crucial role in gastrointestinal colonization, in mucosal symptomatic and asymptomatic infections, in vaginitis, as well as in lethal oroesophageal candidiasis, caused by the combined action of fungal virulence factors and host inflammatory responses when protective immunity is absent. |
基因功能参考文献: | results elucidate HCR-dependent mechanisms for coupling HWP1-dependent gene expression to morphology uniformly in cell populations and prompt the hypothesis that mRNA isoforms may play a role in coupling gene expression to morphology in C. albicans PMID: 29438403 |
亚细胞定位: | Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Hyphal surface. Localizes to the a/a Portion of the conjugation bridge during mating. |
蛋白家族: | HWP1 family |
数据库链接: | KEGG: cal:CAALFM_C403570WA |
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产品名称: | Recombinant Candida albicans Hyphal wall protein 1 (HWP1), partial |
货号: | TSANTI000690 |
纯度: | Greater than 85% as determined by SDS-PAGE. |
基因名: | HWP1 |
Uniprot No.: | P46593 |
别名: | HWP1; ECE2; CAALFM_C403570WA; CaO19.1321; CaO19.8901; Hyphal wall protein 1; Cell elongation protein 2 |
种属: | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
蛋白长度: | Partial |
来源: | Yeast |
分子量: | 21.7 kDa |
表达区域: | 27-203aa |
氨基酸序列 | GQGETEEALIQKRSYDYYQEPCDDYPQQQQQQEPCDYPQQQQQEEPCDYPQQQPQEPCDYPQQPQEPCDYPQQPQEPCDYPQQPQEPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDQPDDNPPIPNIPTDWIPNIPTDWIPDIPEKPTTPATTPNIPA |
蛋白标签: | N-terminal 6xHis-tagged |
产品提供形式: | Liquid or Lyophilized powder |
缓冲液: | Tris-based buffer,50% glycerol |
储存条件: | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
保质期: | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. |
货期: | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
注意事项: | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Datasheet & COA: | Please contact us to get it. |
功能: | Major hyphal cell wall protein which plays a role of adhesin and is required for mating, normal hyphal development, cell-to-cell adhesive functions necessary for biofilm integrity, attachment to host, and virulence. Promotes interactions with host and bacterial molecules, thus leading to effective colonization within polymicrobial communities. Plays a crucial role in gastrointestinal colonization, in mucosal symptomatic and asymptomatic infections, in vaginitis, as well as in lethal oroesophageal candidiasis, caused by the combined action of fungal virulence factors and host inflammatory responses when protective immunity is absent. |
基因功能参考文献: | results elucidate HCR-dependent mechanisms for coupling HWP1-dependent gene expression to morphology uniformly in cell populations and prompt the hypothesis that mRNA isoforms may play a role in coupling gene expression to morphology in C. albicans PMID: 29438403 |
亚细胞定位: | Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Hyphal surface. Localizes to the a/a Portion of the conjugation bridge during mating. |
蛋白家族: | HWP1 family |
数据库链接: | KEGG: cal:CAALFM_C403570WA |