| 产品名称： | pC1R0.9 |
|---|---|
| 商品货号： | TS140915 |
| Designations： | pC1R0.9 |
| GenBank Number： | M14998 |
| Species： | Homo sapiens, human |
| Depositors： | M Lefranc |
| Vector： | Construct size (kb): 3.539999961853027 |
| Insert： | DNA: genomic Insert lengths(kb): 0.8399999737739563 Gene product: T cell receptor, gamma, constant region C1 TCRGC1 Alleles: B1, D4, D2, A1, A2, B2, D1, D3 |
| Insert Size (kb)： | 0.840 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: freeze-dried |
| Comments： | Restriction digests of the clone give the following sizes (kb): EcoRI--2.7, 0.8; HindIII--3.5; BamHI-3.5; PstI--2.8, 0.7; EcoRI/HindIII--2.6, 0.8, 0.1. The 9.4 kb constant band of the PvuII polymorphism corresponds to the TCRGC1 gene. Cross-hybridizes to TCRGC2-exon 3. Subcloned from lambdaD19. Contains exon 3 of TCRGC1. |
| References： | Lefranc MP, Rabbitts TH. Two tandemly organized human genes encoding the T-cell gamma constant-region sequences show multiple rearrangement in difference T-cell types. Nature 316: 464-466, 1985. PubMed: 2991773 Lefranc MP, et al. Rearrangement of two distinct T-cell gamma-chain variable-region genes in human DNA. Nature 319: 420-422, 1986. PubMed: 3003579 Lefranc MP, et al. Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma. Proc. Natl. Acad. Sci. USA 83: 9596-9600, 1986. PubMed: 2879283 Buresi C, et al. Exon duplication and triplication in the human T-cell receptor gamma constant region genes and RFLP in French, Lebanese, Tunisian, and Black African populations. Immunogenetics 29: 161-172, 1989. PubMed: 2564370 Lefranc MP, et al. Molecular mapping of the human T cell receptor gamma (TRG) genes and linkage of the variable and constant regions. Eur. J. Immunol. 19: 989-994, 1989. PubMed: 2526744 Alexandre D, et al. Reciprocal hybrid joints demonstrate successive V - J rearrangements on the same chromosome in the human TCR gamma locus. Int. Immunol. 3: 973-982, 1991. PubMed: 1836738 |
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| 产品名称： | pC1R0.9 |
|---|---|
| 商品货号： | TS140915 |
| Designations： | pC1R0.9 |
| GenBank Number： | M14998 |
| Species： | Homo sapiens, human |
| Depositors： | M Lefranc |
| Vector： | Construct size (kb): 3.539999961853027 |
| Insert： | DNA: genomic Insert lengths(kb): 0.8399999737739563 Gene product: T cell receptor, gamma, constant region C1 TCRGC1 Alleles: B1, D4, D2, A1, A2, B2, D1, D3 |
| Insert Size (kb)： | 0.840 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: freeze-dried |
| Comments： | Restriction digests of the clone give the following sizes (kb): EcoRI--2.7, 0.8; HindIII--3.5; BamHI-3.5; PstI--2.8, 0.7; EcoRI/HindIII--2.6, 0.8, 0.1. The 9.4 kb constant band of the PvuII polymorphism corresponds to the TCRGC1 gene. Cross-hybridizes to TCRGC2-exon 3. Subcloned from lambdaD19. Contains exon 3 of TCRGC1. |
| References： | Lefranc MP, Rabbitts TH. Two tandemly organized human genes encoding the T-cell gamma constant-region sequences show multiple rearrangement in difference T-cell types. Nature 316: 464-466, 1985. PubMed: 2991773 Lefranc MP, et al. Rearrangement of two distinct T-cell gamma-chain variable-region genes in human DNA. Nature 319: 420-422, 1986. PubMed: 3003579 Lefranc MP, et al. Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma. Proc. Natl. Acad. Sci. USA 83: 9596-9600, 1986. PubMed: 2879283 Buresi C, et al. Exon duplication and triplication in the human T-cell receptor gamma constant region genes and RFLP in French, Lebanese, Tunisian, and Black African populations. Immunogenetics 29: 161-172, 1989. PubMed: 2564370 Lefranc MP, et al. Molecular mapping of the human T cell receptor gamma (TRG) genes and linkage of the variable and constant regions. Eur. J. Immunol. 19: 989-994, 1989. PubMed: 2526744 Alexandre D, et al. Reciprocal hybrid joints demonstrate successive V - J rearrangements on the same chromosome in the human TCR gamma locus. Int. Immunol. 3: 973-982, 1991. PubMed: 1836738 |
