| 产品名称： | Streptomyces avermitilis (ex Burg et al.) Kim and Goodfellow |
|---|---|
| 商品货号： | TS147425 |
| Deposited As： | Streptomyces avermitilis |
| Strain Designations： | MA-4848 |
| Application： | Produces avermectin avermectins Produces avermectin B(1)a C-076 Produces C-076 and derivatives |
| Isolation： | Mutant derived from ATCC 31267 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Storage Conditions： | 2°C to 8°C |
| Disclosure： | This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. |
| Preceptrol®： | no |
| Type Strain： | no |
| Medium： | ATCC® Medium 965: Tomato-dextrin-yeast medium |
| Growth Conditions： | Temperature: 26.0°C Atmosphere:xa0 Aerobicxa0 |
| Name of Depositor： | Merck & Co., Inc. |
| U.S. Patent Number： | |
| References： | Ormond RE. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use. US Patent 4,412,991 dated Nov 1 1983 Hafner EW, et al. Cultures for production of B avermectins. US Patent 5,565,359 dated Oct 15 1996 Goegelman RT, et al. Novel C-076 compounds. US Patent 4,378,353 dated Mar 26 1983 |
| Cross References： | Nucleotide (GenBank) : U11864 Streptomyces avermitilis TS147425 4-hydroxyphenylpyruvate acid dioxygenase gene, complete cds. Nucleotide (GenBank) : U26308 Streptomyces avermitilis branched-chain alpha-keto acid dehydrogenase E1-alpha subunit gene, complete cds. Nucleotide (GenBank) : U17169 Streptomyces avermitilis E1-alpha branched-chain alpha keto acid dehydrogenase (bkdA) gene, complete cds, E1-beta branched-chain alpha keto acid dehydrogenase (bkdB) gene, complete cds, and E2 branched-chain alpha keto acid dehydrogenase (bkdC) |
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| 产品名称： | Streptomyces avermitilis (ex Burg et al.) Kim and Goodfellow |
|---|---|
| 商品货号： | TS147425 |
| Deposited As： | Streptomyces avermitilis |
| Strain Designations： | MA-4848 |
| Application： | Produces avermectin avermectins Produces avermectin B(1)a C-076 Produces C-076 and derivatives |
| Isolation： | Mutant derived from ATCC 31267 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Storage Conditions： | 2°C to 8°C |
| Disclosure： | This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC. |
| Preceptrol®： | no |
| Type Strain： | no |
| Medium： | ATCC® Medium 965: Tomato-dextrin-yeast medium |
| Growth Conditions： | Temperature: 26.0°C Atmosphere:xa0 Aerobicxa0 |
| Name of Depositor： | Merck & Co., Inc. |
| U.S. Patent Number： | |
| References： | Ormond RE. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use. US Patent 4,412,991 dated Nov 1 1983 Hafner EW, et al. Cultures for production of B avermectins. US Patent 5,565,359 dated Oct 15 1996 Goegelman RT, et al. Novel C-076 compounds. US Patent 4,378,353 dated Mar 26 1983 |
| Cross References： | Nucleotide (GenBank) : U11864 Streptomyces avermitilis TS147425 4-hydroxyphenylpyruvate acid dioxygenase gene, complete cds. Nucleotide (GenBank) : U26308 Streptomyces avermitilis branched-chain alpha-keto acid dehydrogenase E1-alpha subunit gene, complete cds. Nucleotide (GenBank) : U17169 Streptomyces avermitilis E1-alpha branched-chain alpha keto acid dehydrogenase (bkdA) gene, complete cds, E1-beta branched-chain alpha keto acid dehydrogenase (bkdB) gene, complete cds, and E2 branched-chain alpha keto acid dehydrogenase (bkdC) |
