| 产品名称： | Mycobacterium ulcerans MacCallum et al. |
|---|---|
| 商品货号： | TS165793 |
| Strain Designations： | NCTC 10417 ATCC 14188, DSM 44154, RT, TMC 1617 |
| Isolation： | Pus from leg ulcer |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | frozen |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Preceptrol®： | no |
| Type Strain： | yes |
| Comments： | This strain demonstrates reduced virulence in mice and does not produce mycolactone. |
| Medium： | ATCC® Medium 1395: Middlebrook 7H9 broth with ADC enrichment ATCC® Medium 173: Middlebrook 7H10 agar with Middlebrook OADC enrichment ATCC® Medium 90: Lowenstein Jenson medium |
| Growth Conditions： | Temperature: 30°C
Atmosphere: Aerobic |
| Name of Depositor： | NCTC |
| Special Collection： | NCRR Contract |
| Chain of Custody： | ATCC |
| References： | Bentoucha A, et al. Activities of new macrolides and fluoroquinolones against Mycobacterium ulcerans infection in mice. Antimicrob. Agents Chemother. 45(11): 3109-3112, 2001. PubMed: 11600364 Bonicke R. Identification of mycobacteria by biochemical methods. Bull. Int. Union Tuberc. 32: 13-68, 1962. Bull. Int. Union Tuberc. 30: 202, 1960. Dega H, et al. Bactericidal activity of rifampin-amikacin against Mycobacterium ulcerans in mice. Antimicrob. Agents Chemother. 46(10): 3193-3196, 2002. PubMed: 12234844 Dega H, et al. Activities of several antimicrobials against Mycobacterium ulcerans infection in mice. Antimicrob. Agents Chemother. 44(9): 2367-2372, 2000. PubMed: 10952581 Fenner, F. The pathogenic behavior of Mycobacterium ulcerans and Mycobacterium balnei in the mouse and the developing chick embryo. Am. Rev. Tuberc. 73(5): 650-673, 1956. Fenner F. The significance of the incubation period in infectious diseases. Med. J. Aust. 2: 813-818, 1950. PubMed: 14796139 Fenner F, Leach RH. Studies on Mycobacterium ulcerans. I. Serological relationship to other mycobacteria. Aust. J. Exp. Biol. Med. Sci. 30: 1-10, 1952. Fenner F, Leach RH. Studies on Mycobacterium ulcerans. II. Cross reactivity in guinea pigs sensitized with Mycobacterium ulcerans and other mycobacteriium. Aust. J. Exp. Biol. Med. Sci. 30: 11-20, 1952. George KM, et al. Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence. Science. 283(5403): 854-857, 1999. PubMed: 9933171 George KM, Pascopella L, Welty DM, Small PL. A Mycobacterium ulcerans toxin, mycolactone, causes apoptosis in guinea pig ulcers and tissue culture cells. Infect. Immun. 68(2): 877-883, 2000. PubMed: 10639458 Lapage SP, et al. Annotations from the FCTC on the list of type and reference strains of bacteria, Sneath and Skerman 1966. Int. J. Syst. Bacteriol. 17: 93-103, 1967. MacCallum P. A new mycobacterial infection in man. I. Clinical aspects. J. Pathol. Bacteriol. 60: 93-122, 1948. P Converse, personal communication Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980. Sneath PH, Skerman VB. A list of type and reference strains of bacteria. Int. J. Syst. Bacteriol. 16: 1-134, 1966. Stinear TP, et al. Common evolutionary origin for the unstable virulence plasmid pMUM found in geographically diverse strains of Mycobacterium ulcerans. J. Bacteriol. 187(5): 1668-1676, 2005. PubMed: 15716437 |
| Cross References： | Nucleotide (GenBank) : AJ271681 Mycobacterium ulcerans tlyA gene for putative haemolysin. Nucleotide (GenBank) : X99217 M.ulcerans internal transcribed spacer between 16S and 23S rRNA, genomic sequence. |
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| 产品名称： | Mycobacterium ulcerans MacCallum et al. |
|---|---|
| 商品货号： | TS165793 |
| Strain Designations： | NCTC 10417 ATCC 14188, DSM 44154, RT, TMC 1617 |
| Isolation： | Pus from leg ulcer |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | frozen |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Preceptrol®： | no |
| Type Strain： | yes |
| Comments： | This strain demonstrates reduced virulence in mice and does not produce mycolactone. |
| Medium： | ATCC® Medium 1395: Middlebrook 7H9 broth with ADC enrichment ATCC® Medium 173: Middlebrook 7H10 agar with Middlebrook OADC enrichment ATCC® Medium 90: Lowenstein Jenson medium |
| Growth Conditions： | Temperature: 30°C
Atmosphere: Aerobic |
| Name of Depositor： | NCTC |
| Special Collection： | NCRR Contract |
| Chain of Custody： | ATCC |
| References： | Bentoucha A, et al. Activities of new macrolides and fluoroquinolones against Mycobacterium ulcerans infection in mice. Antimicrob. Agents Chemother. 45(11): 3109-3112, 2001. PubMed: 11600364 Bonicke R. Identification of mycobacteria by biochemical methods. Bull. Int. Union Tuberc. 32: 13-68, 1962. Bull. Int. Union Tuberc. 30: 202, 1960. Dega H, et al. Bactericidal activity of rifampin-amikacin against Mycobacterium ulcerans in mice. Antimicrob. Agents Chemother. 46(10): 3193-3196, 2002. PubMed: 12234844 Dega H, et al. Activities of several antimicrobials against Mycobacterium ulcerans infection in mice. Antimicrob. Agents Chemother. 44(9): 2367-2372, 2000. PubMed: 10952581 Fenner, F. The pathogenic behavior of Mycobacterium ulcerans and Mycobacterium balnei in the mouse and the developing chick embryo. Am. Rev. Tuberc. 73(5): 650-673, 1956. Fenner F. The significance of the incubation period in infectious diseases. Med. J. Aust. 2: 813-818, 1950. PubMed: 14796139 Fenner F, Leach RH. Studies on Mycobacterium ulcerans. I. Serological relationship to other mycobacteria. Aust. J. Exp. Biol. Med. Sci. 30: 1-10, 1952. Fenner F, Leach RH. Studies on Mycobacterium ulcerans. II. Cross reactivity in guinea pigs sensitized with Mycobacterium ulcerans and other mycobacteriium. Aust. J. Exp. Biol. Med. Sci. 30: 11-20, 1952. George KM, et al. Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence. Science. 283(5403): 854-857, 1999. PubMed: 9933171 George KM, Pascopella L, Welty DM, Small PL. A Mycobacterium ulcerans toxin, mycolactone, causes apoptosis in guinea pig ulcers and tissue culture cells. Infect. Immun. 68(2): 877-883, 2000. PubMed: 10639458 Lapage SP, et al. Annotations from the FCTC on the list of type and reference strains of bacteria, Sneath and Skerman 1966. Int. J. Syst. Bacteriol. 17: 93-103, 1967. MacCallum P. A new mycobacterial infection in man. I. Clinical aspects. J. Pathol. Bacteriol. 60: 93-122, 1948. P Converse, personal communication Skerman VB, et al. Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420, 1980. Sneath PH, Skerman VB. A list of type and reference strains of bacteria. Int. J. Syst. Bacteriol. 16: 1-134, 1966. Stinear TP, et al. Common evolutionary origin for the unstable virulence plasmid pMUM found in geographically diverse strains of Mycobacterium ulcerans. J. Bacteriol. 187(5): 1668-1676, 2005. PubMed: 15716437 |
| Cross References： | Nucleotide (GenBank) : AJ271681 Mycobacterium ulcerans tlyA gene for putative haemolysin. Nucleotide (GenBank) : X99217 M.ulcerans internal transcribed spacer between 16S and 23S rRNA, genomic sequence. |
