| 产品名称： | Umbelopsis isabellina (Oudemans) Gams |
|---|---|
| 商品货号： | TS183049 |
| Deposited As： | Mortierella isabellina Oudemans |
| Strain Designations： | NRRL 1757 |
| Application： | Hydroxylates ethylbenzene
Hydroxylates progesterone
Oxidizes alkyl benzyl sulfide
Oxidizes bibenzyl
Oxidizes organic sulphides
Produces (+)-(3R)-ethyl 3-hydroxy-3-(3,4-dimethoxyphenyl) propionate
Produces (S)-4-hydroxy-alpha-lapachone
Produces benzylic hydroxylase
Produces chiral isothiocyanate sulfoxides
Produces chroman-4-ol
Produces thiochroman-4-ol
Reduces chromanone
Reduces thiochromanone
Sulfoxidates methylphenylsulfide thioanisole
Transforms organophosphines
Conversion of olefins to vicinal diols |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain： | no |
| Preceptrol®： | no |
| Comments： | Morphology |
| Medium： | ATCC® Medium 336: Potato dextrose agar (PDA) ATCC® Medium 325: Malt extract agar (Blakeslees formula) |
| Growth Conditions： | Temperature: 24°C to 26°C Atmosphere: Typical aerobic |
| Sequenced Data： |
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence AAGGATCATTACCAAAAGATAATCTTTCAAATCGAAAGATCTTTTCCTTTGTGCTGGCTTTGACCGTATGTAATTTTGGGACTTAAACATGGTAGCTTTTTTGTTACCGGTCCCAAAAACAATTATATCATCCTTATGAAAAACTTACTGAACAACTAAACAATGATTTTAATAATCTGTTTAAAACAACTTTCAACAACGGATCTCTTGGTTCTCGCATCGATGAAGAACGCAGCGAAATGCGATACGTAATGTGAATTGCAGAATTCAGTGAATCATCGAATCTTTGAACGCACATTGCACTCCTTGGTATTCCGAGGAGTATGCCTGTTTCAGTATCATGAGCACTCTCACACCTAACCTTTGGGTTTTGTTGTGGAATTGGGATGCGCCGATTTTAATAGTCGGCACTCCTAAAATGTAGTTCTTGGCTGTTTCCTACTACAGCAGTTTGGCCTAATAGTTTTGACTTTTGTCAAATCTTTGGCTACATTTGCTTCTGGAAATCAGTYTTGATAATACAGAAAACTCATTCAAACTTTGATCTGAAATCAGGTAGGGCTACCCGCTGAACTTAAG D1D2 region of the 28S ribosomal RNA gene CATATCAATAAGCGGAGGAAAAGAAACTAACAAGGATTCCCCTAGTAACGGCGAGTGAAGCGGGAAGAGCTCAAATTTAAAATCTGGCTTGCTTGCAAGTCCGAGTTGTAGTCTGAAGAAGCGTTTTCCATGAAAGCTGAGGCACAAGTCCTTTGGAACAGGGCATCATAGAGGGTGAGAATCCCGTCCATGGTCTCATGCATTTCATTTTGTGATACGTTTTCTAAGAGTCAGGTTGTTTGGGAATGCAGCCTAAAATGGGTGGTAAATTTCATCTAAAGCTAAATATTGGCGAGAGACCGATAGCGAACAAGTACCGTGAGGGAAAGATGAAAAGAACTTTGAAAAGAGAGTTAAAAAGTACGTGAAATTGTTGAAAGGGAACCGTTTGAAGCCAGTCTTGCTTACTTGTGATCAATCTTAGCTTCGGCTTGGATGCACTCTCAAGTTATGCAGGTCAACGTCAGTTTGAGAGGTGGGAAAAAAGTTTGAGGAATGTGGCCTTCGGGTGTTATAGCCTCTTACTAAATACCATCTCCTGGACTGAGGCTCGCAGCAAAAATGTGGGCTGGTTTGCTCCTGAGGTGAATCATTATTAAGACAGCTTGCTGACTTAGTTTTGTGGATCTTCACGGTAGGCTAGCTTCTAATTTGCTTAGGTCGTTGACATAATGGCTTTAAATGA |
| Name of Depositor： | NRRL |
| References： | . . Biocatalysis 10: 65-76, 1994. Holland HL, et al. Preparation of homochiral chroman-4-ols and thiochroman-4-ols by microbial biotransformation. Tetrahedron Asymmetry 2: 335-338, 1991. Holland HL, et al. Biotransformation of organic sulfides. Part 7. Formation of chiral isothiocyanate sulfoxides and related compounds by microbial biotransformation. Tetrahedron Asymmetry 6: 1569-1574, 1995. Bardot V, et al. Microbial synthesis of (+)-(3R)-ethyl 3-hydroxy-3-(3,4-dimethoxyphenyl)propionate. Tetrahedron Asymmetry 7: 1077-1088, 1996. Holland HL, et al. Microbial oxidation of benzyl sulfides and bibenzyl by Mortierella isabellina and Helminthosporium species. Can. J. Chem. 69: 1989-1993, 1991. . . Can. J. Chem. 73: 1399-1405, 1995. ODonnell KL. Zygomycetes in culture. Athens, GA: Univ. Georgia; 1979 Holland HL, et al. Fungal hydroxylation of ethyl benzene and derivatives. Tetrahedron Lett. 26: 6409-6412, 1985. Holland HL, et al. The oxidation of organic sulphides by Mortierella isabellina. 2. Effects of substituents on the stereochemistry of sulphoxide formation. Can. J. Chem. 63: 1118-1120, 1985. Holland HL, et al. Fungal biotransformation of organophosphines. Xenobiotica 23: 519-524, 1993. PubMed: 8342299 Holland HL, et al. Side chain hydroxylation of aromatic compounds by fungi. Part 5. Exploring the benzylic hydroxylase of Mortierella isabellina. Tetrahedron Asymmetry 4: 1353-1364, 1993. Holland HL, et al. Effect of cell immobilization and organic solvents on sulfoxidation and steroid hydroxylation by Mortierella isabellina. J. Ind. Microbiol. 10: 195-197, 1992. PubMed: 1368869 |
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| 产品名称： | Umbelopsis isabellina (Oudemans) Gams |
|---|---|
| 商品货号： | TS183049 |
| Deposited As： | Mortierella isabellina Oudemans |
| Strain Designations： | NRRL 1757 |
| Application： | Hydroxylates ethylbenzene
Hydroxylates progesterone
Oxidizes alkyl benzyl sulfide
Oxidizes bibenzyl
Oxidizes organic sulphides
Produces (+)-(3R)-ethyl 3-hydroxy-3-(3,4-dimethoxyphenyl) propionate
Produces (S)-4-hydroxy-alpha-lapachone
Produces benzylic hydroxylase
Produces chiral isothiocyanate sulfoxides
Produces chroman-4-ol
Produces thiochroman-4-ol
Reduces chromanone
Reduces thiochromanone
Sulfoxidates methylphenylsulfide thioanisole
Transforms organophosphines
Conversion of olefins to vicinal diols |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain： | no |
| Preceptrol®： | no |
| Comments： | Morphology |
| Medium： | ATCC® Medium 336: Potato dextrose agar (PDA) ATCC® Medium 325: Malt extract agar (Blakeslees formula) |
| Growth Conditions： | Temperature: 24°C to 26°C Atmosphere: Typical aerobic |
| Sequenced Data： |
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence AAGGATCATTACCAAAAGATAATCTTTCAAATCGAAAGATCTTTTCCTTTGTGCTGGCTTTGACCGTATGTAATTTTGGGACTTAAACATGGTAGCTTTTTTGTTACCGGTCCCAAAAACAATTATATCATCCTTATGAAAAACTTACTGAACAACTAAACAATGATTTTAATAATCTGTTTAAAACAACTTTCAACAACGGATCTCTTGGTTCTCGCATCGATGAAGAACGCAGCGAAATGCGATACGTAATGTGAATTGCAGAATTCAGTGAATCATCGAATCTTTGAACGCACATTGCACTCCTTGGTATTCCGAGGAGTATGCCTGTTTCAGTATCATGAGCACTCTCACACCTAACCTTTGGGTTTTGTTGTGGAATTGGGATGCGCCGATTTTAATAGTCGGCACTCCTAAAATGTAGTTCTTGGCTGTTTCCTACTACAGCAGTTTGGCCTAATAGTTTTGACTTTTGTCAAATCTTTGGCTACATTTGCTTCTGGAAATCAGTYTTGATAATACAGAAAACTCATTCAAACTTTGATCTGAAATCAGGTAGGGCTACCCGCTGAACTTAAG D1D2 region of the 28S ribosomal RNA gene CATATCAATAAGCGGAGGAAAAGAAACTAACAAGGATTCCCCTAGTAACGGCGAGTGAAGCGGGAAGAGCTCAAATTTAAAATCTGGCTTGCTTGCAAGTCCGAGTTGTAGTCTGAAGAAGCGTTTTCCATGAAAGCTGAGGCACAAGTCCTTTGGAACAGGGCATCATAGAGGGTGAGAATCCCGTCCATGGTCTCATGCATTTCATTTTGTGATACGTTTTCTAAGAGTCAGGTTGTTTGGGAATGCAGCCTAAAATGGGTGGTAAATTTCATCTAAAGCTAAATATTGGCGAGAGACCGATAGCGAACAAGTACCGTGAGGGAAAGATGAAAAGAACTTTGAAAAGAGAGTTAAAAAGTACGTGAAATTGTTGAAAGGGAACCGTTTGAAGCCAGTCTTGCTTACTTGTGATCAATCTTAGCTTCGGCTTGGATGCACTCTCAAGTTATGCAGGTCAACGTCAGTTTGAGAGGTGGGAAAAAAGTTTGAGGAATGTGGCCTTCGGGTGTTATAGCCTCTTACTAAATACCATCTCCTGGACTGAGGCTCGCAGCAAAAATGTGGGCTGGTTTGCTCCTGAGGTGAATCATTATTAAGACAGCTTGCTGACTTAGTTTTGTGGATCTTCACGGTAGGCTAGCTTCTAATTTGCTTAGGTCGTTGACATAATGGCTTTAAATGA |
| Name of Depositor： | NRRL |
| References： | . . Biocatalysis 10: 65-76, 1994. Holland HL, et al. Preparation of homochiral chroman-4-ols and thiochroman-4-ols by microbial biotransformation. Tetrahedron Asymmetry 2: 335-338, 1991. Holland HL, et al. Biotransformation of organic sulfides. Part 7. Formation of chiral isothiocyanate sulfoxides and related compounds by microbial biotransformation. Tetrahedron Asymmetry 6: 1569-1574, 1995. Bardot V, et al. Microbial synthesis of (+)-(3R)-ethyl 3-hydroxy-3-(3,4-dimethoxyphenyl)propionate. Tetrahedron Asymmetry 7: 1077-1088, 1996. Holland HL, et al. Microbial oxidation of benzyl sulfides and bibenzyl by Mortierella isabellina and Helminthosporium species. Can. J. Chem. 69: 1989-1993, 1991. . . Can. J. Chem. 73: 1399-1405, 1995. ODonnell KL. Zygomycetes in culture. Athens, GA: Univ. Georgia; 1979 Holland HL, et al. Fungal hydroxylation of ethyl benzene and derivatives. Tetrahedron Lett. 26: 6409-6412, 1985. Holland HL, et al. The oxidation of organic sulphides by Mortierella isabellina. 2. Effects of substituents on the stereochemistry of sulphoxide formation. Can. J. Chem. 63: 1118-1120, 1985. Holland HL, et al. Fungal biotransformation of organophosphines. Xenobiotica 23: 519-524, 1993. PubMed: 8342299 Holland HL, et al. Side chain hydroxylation of aromatic compounds by fungi. Part 5. Exploring the benzylic hydroxylase of Mortierella isabellina. Tetrahedron Asymmetry 4: 1353-1364, 1993. Holland HL, et al. Effect of cell immobilization and organic solvents on sulfoxidation and steroid hydroxylation by Mortierella isabellina. J. Ind. Microbiol. 10: 195-197, 1992. PubMed: 1368869 |
