| 产品名称： | CRI-pS232 |
|---|---|
| 商品货号： | TS184160 |
| Designations： | CRI-pS232 |
| Species： | Homo sapiens, human |
| Depositors： | Collaborative Research, Inc. |
| Vector： | Construct size (kb): 9.399999618530273 |
| Insert： | DNA: genomic Insert lengths(kb): 6.699999809265137 Gene product: DNA Segment, numerous copies, homologous on X and Y DXS278 |
| Insert Size (kb)： | 6.700 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments： | Restriction digests of the clone give the following sizes (kb): EcoRI--6.2, 2.7; BamHI--8.9; HindIII--7.65, 1.25; PstI--8.9; BglII--6.7, 2.2. DXS278 is linked to X-linked Kallmann syndrome with theta max = 0.03, LOD score = 6.5. The probe detects constant bands of 15, 5.9, and 3.5 kb on the Y chromosome for the EcoRI polymorphism. This is a subclone of CRI-S232. |
| References： | Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638 Barker D, et al. Genetic linkage map of human chromosome 7 with 63 DNA markers. Proc. Natl. Acad. Sci. USA 84: 8006-8010, 1987. PubMed: 2891136 Knowlton RG, et al. An extremely polymorphic locus on the short arm of the human X chromosome with homology to the long arm of the Y chromosome. Nucleic Acids Res. 17: 423-437, 1989. PubMed: 2911472 Meitinger T, et al. Definitive localization of X-linked Kallmann syndrome (hypogonadotropic hypogonadism and anosmia) to Xp22.3: close linkage to the hypervariable repeat sequence CRI-S232. Am. J. Hum. Genet. 47: 664-669, 1990. PubMed: 1977309 Schwartz CE, et al. Allan-Herndon syndrome. II. Linkage to DNA markers in Xq21. Am. J. Hum. Genet. 47: 454-458, 1990. PubMed: 2393020 Ballabio A, et al. Two families of low-copy-number repeats are interspersed on Xp22.3: implications for the high frequency of deletions in this region. Genomics 8: 263-270, 1990. PubMed: 2249849 Schnur RE, et al. Partial deletions of a sequence family ("DXS278") and its physical linkage to steroid sulfatase as detected by pulsed-field gel electrophoresis. Genomics 8: 255-262, 1990. PubMed: 1979048 |
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| 产品名称： | CRI-pS232 |
|---|---|
| 商品货号： | TS184160 |
| Designations： | CRI-pS232 |
| Species： | Homo sapiens, human |
| Depositors： | Collaborative Research, Inc. |
| Vector： | Construct size (kb): 9.399999618530273 |
| Insert： | DNA: genomic Insert lengths(kb): 6.699999809265137 Gene product: DNA Segment, numerous copies, homologous on X and Y DXS278 |
| Insert Size (kb)： | 6.700 |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Shipping Information： | Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
| Comments： | Restriction digests of the clone give the following sizes (kb): EcoRI--6.2, 2.7; BamHI--8.9; HindIII--7.65, 1.25; PstI--8.9; BglII--6.7, 2.2. DXS278 is linked to X-linked Kallmann syndrome with theta max = 0.03, LOD score = 6.5. The probe detects constant bands of 15, 5.9, and 3.5 kb on the Y chromosome for the EcoRI polymorphism. This is a subclone of CRI-S232. |
| References： | Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638 Barker D, et al. Genetic linkage map of human chromosome 7 with 63 DNA markers. Proc. Natl. Acad. Sci. USA 84: 8006-8010, 1987. PubMed: 2891136 Knowlton RG, et al. An extremely polymorphic locus on the short arm of the human X chromosome with homology to the long arm of the Y chromosome. Nucleic Acids Res. 17: 423-437, 1989. PubMed: 2911472 Meitinger T, et al. Definitive localization of X-linked Kallmann syndrome (hypogonadotropic hypogonadism and anosmia) to Xp22.3: close linkage to the hypervariable repeat sequence CRI-S232. Am. J. Hum. Genet. 47: 664-669, 1990. PubMed: 1977309 Schwartz CE, et al. Allan-Herndon syndrome. II. Linkage to DNA markers in Xq21. Am. J. Hum. Genet. 47: 454-458, 1990. PubMed: 2393020 Ballabio A, et al. Two families of low-copy-number repeats are interspersed on Xp22.3: implications for the high frequency of deletions in this region. Genomics 8: 263-270, 1990. PubMed: 2249849 Schnur RE, et al. Partial deletions of a sequence family ("DXS278") and its physical linkage to steroid sulfatase as detected by pulsed-field gel electrophoresis. Genomics 8: 255-262, 1990. PubMed: 1979048 |
