| 产品名称： | Aspergillus niger van Tieghem |
|---|---|
| 商品货号： | TS200531 |
| Strain Designations： | NRRL 599 Doelger 2, IMI 41874, X-172 |
| Application： | Degrades acronine acronycine
Degrades apple pomace
Degrades brewery wastes
Degrades cotton wastes
Degrades inulin
Degrades molasses
Degrades pineapple wastes
Produces 12-hydroxy-trans-nerolidol
Produces 18-homo-19-norcortisone
Produces 18-homo-19-norhydrocortisone
Produces 9-hydroxyacronycine
Produces L-malic acid
Produces citric acid citrate
Produces gluconic acid
Produces grindelane dimers
Produces hydroxygrindelanes
Produces hydroxylated biphenyl compounds
Produces hydroxylated steroids steroids, hydroxylated
Produces lipase
Reduces 3,5-dimethoxycinnamic acid
Reduces 3-methobenzoic acid
Reduces 3-methoxy-8(14)-seco-1,3,5(10),9(11)-estratetraene-14,17-dione
Transforms acronine acronycine
Transforms chromanone
Transforms flavonoids |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain： | no |
| Preceptrol®： | no |
| Medium： | ATCC® Medium 200: YM agar or YM broth ATCC® Medium 323: Malt agar medium ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions： | Temperature: 24°C to 26°C Atmosphere: Typical aerobic |
| Sequenced Data： |
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence
GGTTTCCGTAGGTGAACCTGCGGAAGGATCATTACCGAGTGCGGGTCCTTTGGGCCCAACCTCCCATCCGTGTCTATTGTACCCTGTTGCTTCGGCGGGCCCGCCGCTTGTCGGCCGCCGGGGGGGCGCCTCTGCCCCCCGGGCCCGTGCCCGCCGGAGACCCCAACACGAACACTGTCTGAAAGCGTGCAGTCTGAGTTGATTGAATGCAATCAGTTAAAACTTTCAACAATGGATCTCTTGGTTCCGGCATCGATGAAGAACGCAGCGAAATGCGATAACTAATGTGAATTGCAGAATTCAGTGAATCATCGAGTCTTTGAACGCACATTGCGCCCCCTGGTATTCCGGGGGGCATGCCTGTCCGAGCGTCATTGCTGCCCTCAAGCCCGGCTTGTGTGTTGGGTCGCCGTCCCCCTCTCCGGGGGGACGGGCCCGAAAGGCAGCGGCGGCACCGCGTCCGATCCTCGAGCGTATGGGGCTTTGTCACATGCTCTGTAGGATTGGCCGGCGCCTGCCGACGTTTTCCAACCATTCTTTCCAGGTTGACCTCGGATCAGGTAGGGATACCCGCTGAACTTAAGCATATCAATAA D1D2 region of the 28S ribosomal RNA gene ATATCAATAAGCGGAGGAAAAGAAACCAACCGGGATTGCCTCAGTAACGGCGAGTGAAGCGGCAAGAGCTCAAATTTGAAAGCTGGCTCCTTCGGAGTCCGCATTGTAATTTGCAGAGGATGCTTTGGGTGCGGCCCCCGTCTAAGTGCCCTGGAACGGGCCGTCAGAGAGGGTGAGAATCCCGTCTTGGGCGGGGTGTCCGTGCCCGTGTAAAGCTCCTTCGACGAGTCGAGTTGTTTGGGAATGCAGCTCTAAATGGGTGGTAAATTTCATCTAAAGCTAAATACTGGCCGGAGACCGATAGCGCACAAGTAGAGTGATCGAAAGATGAAAAGCACTTTGAAAAGAGAGTTAAACAGCACGTGAAATTGTTGAAAGGGAAGCGCTTGCGACCAGACTCGCCCGCGGGGTTCAGCCGGCATTCGTGCCGGTGTACTTCCCCGTGGGCGGGCCAGCGTCGGTTTGGGCGGCCGGTCAAAGGCCCCTGGAATGTAGTGCCCTCCGGGGCACCTTATAGCCAGGGGTGCAATGCGGCCAGCCTGGACCGAGGAACGCGCTTCGGCACGGACGCTGGCATAATGGTCGTAAACGAC beta-tubulin gene TTGCCCTCCCCGTCCCTCGTCCGTCAGGAGACGCGTCGTTGGTTGGCATCTCTTTTGCTCGGGACCCCACCGGTTCTTCGACCAACTCATTCTTGTGCTAACTGCATGTCTTCTTCGCTTCATAGGTTCACCTCCAAACCGGCCAGTGTGTAAGTGCCAATATATGCTTCGGATGATTGCCCCCAAGGGTCTTGATTGGTGTTTGGTGGACTAAACAATATATCATGGTGGTTAGGGTAACCAAATTGGTGCTGCTTTCTGGTACGTATACAACTGCCATTGGATTGGGGATGGAACATCGTCTCTTAGGCTATCTCAGCTTGAGTTCAGATGTTGTCCATTAGGTACATGCTATCGGTCTAAGAACACGTCTAACAATTCAACAGGCAGACCATCTCTGGCGAGCACGGCCTTGACGGCTCCGGTGTGTAAGTGCAACTTTTTCACACCTCTCAATTGGTCAACAATGGGCAAAGGGTTGGGTCTTCTGACACGCAGGATAGTTACAATGGCACCTCCGACCTCCAGCTGGAGCGCATGAACGTCTACTTCAACGAGGTGAGATCCATCGGACCTTGGCTTTTTCACGACAATATCATCAATGTCCTAATCACTTCAGCAGGCTAGCGGTAACAAGTATGTTCCTCGTGCCGTCCTCGTCGACCTCGAGCCCGGTACCATGGACGCCGTCCGTGCCGGTCCTTTCGGCCAGCTCTTCCGCCCCGACAACTTCGTCTTCGGCCAGTCCGGTGCTGGTAACAACTGG |
| Name of Depositor： | NRRL |
| Chain of Custody： | ATCC <-- NRRL <-- A.J. Moyer strain Doelger 2 |
| References： | Bercovitz A, et al. Localization of pyruvate carboxylase in organic acid-producing Aspergillus strains. Appl. Environ. Microbiol. 56: 1594-1597, 1990. PubMed: 2383004 Schwartz RD. Microbial production of hydroxylated biphenyl compounds. US Patent 4,153,509 dated May 8 1979 Gadsby B, Greenspan G. C-21 hydroxylation products of steroids. US Patent 3,529,000 dated Sep 15 1970 Gibian H, et al. Production of optically active antipodes. US Patent 3,562,112 dated Feb 9 1971 Arfmann HA, Abraham WR. Microbial reduction of aromatic carboxylic acids. Z. Naturforsch. Sect. C Biosci. 48: 52-57, 1993. Auret BJ, Holland HL. Microbiological 18-hydroxylation of steroids. J. Chem. Soc. Commun. 1195: 1157, 1971. Roukas T. Production of citric acid from beet molasses by immobilized cells of Aspergillus niger. J. Food Sci. 56: 878-880, 1991. Drysdale CR, McKay AM. Citric acid production by Aspergillus niger in surface culture on inulin. Lett. Appl. Microbiol. 20: 252-254, 1995. PubMed: 7766122 Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of chromone, chromanone, and ring A hydroxyflavones. J. Nat. Prod. 53: 1471-1478, 1990. PubMed: 2089118 Tran CT, et al. Selection of a strain of Aspergillus for the production of citric acid from pineapple waste in solid-state fermentation. World J. Microbiol. Biotechnol. 14: 399-404, 1998. Heinrich M, Rehm HJ. Formation of gluconic acid at low pH-values by free and immobilized Aspergillus niger during citric acid fermentation. Eur. J. Appl. Microbiol. Biotechnol. 15: 88-92, 1982. Doelger WP, Prescott SC. Citric acid fermentation. Ind. Eng. Chem. 26: 1142-1149, 1934. Betts RE, et al. Microbial transformations of antitumor compounds. I. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602, 1974. PubMed: 4829940 Hang YD, Woodams EE. Apple pomace: a potential substrate for citric acid production by Aspergillus niger. Biotechnol. Lett. 6: 763-764, 1984. Roukas T, Kotzekidon P. Production of citric acid from brewery wastes by surface fermentation using Aspergillus niger. J. Food Sci. 51: 225-228, 1986. Hoffmann JJ, et al. Hydroxygrindelane derivatives by microbial transformation. Phytochemistry 27: 2125-2127, 1988. Arfmann HA, et al. Microbial omega-hydroxylation of trans-nerolidol and structurally related sesquiterpenoids. Biocatalysis 2: 59-67, 1988. Roukas T, Alichanidis E. Citric acid production from beet molasses by cell cycle of Aspergillus niger. J. Ind. Microbiol. 7: 71-74, 1991. Hoffmann JJ, et al. Formation of grindelane dimers by microbial transformation. Phytochemistry 31: 3045-3049, 1992. Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of (+/-)-flavanone and (+/-)-isoflavanone. J. Nat. Prod. 53: 644-656, 1990. PubMed: 2213034 Miura S, et al. Prostaglandin chemistry -- IV. Microbiological kinetic resolution and asymmetric hydrolysis of 3,5-diacetoxycyclopent-1-ene. Tetrahedron 32: 1893-1898, 1976. Kiel H, et al. Citric acid fermentation by Aspergillus niger on low sugar concentrations and cotton waste. Appl. Environ. Microbiol. 42: 1-4, 1981. Martinez-Culebras PV, et al. Molecular characterization of the black Aspergillus isolates responsible for ochratoxin A contamination in grapes and wine in relation to taxonomy of Aspergillus section Nigri. Int. J. Food Microbiol. 132: 33-41, 2009. PubMed: 19401261 |
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| 产品名称： | Aspergillus niger van Tieghem |
|---|---|
| 商品货号： | TS200531 |
| Strain Designations： | NRRL 599 Doelger 2, IMI 41874, X-172 |
| Application： | Degrades acronine acronycine
Degrades apple pomace
Degrades brewery wastes
Degrades cotton wastes
Degrades inulin
Degrades molasses
Degrades pineapple wastes
Produces 12-hydroxy-trans-nerolidol
Produces 18-homo-19-norcortisone
Produces 18-homo-19-norhydrocortisone
Produces 9-hydroxyacronycine
Produces L-malic acid
Produces citric acid citrate
Produces gluconic acid
Produces grindelane dimers
Produces hydroxygrindelanes
Produces hydroxylated biphenyl compounds
Produces hydroxylated steroids steroids, hydroxylated
Produces lipase
Reduces 3,5-dimethoxycinnamic acid
Reduces 3-methobenzoic acid
Reduces 3-methoxy-8(14)-seco-1,3,5(10),9(11)-estratetraene-14,17-dione
Transforms acronine acronycine
Transforms chromanone
Transforms flavonoids |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | freeze-dried |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain： | no |
| Preceptrol®： | no |
| Medium： | ATCC® Medium 200: YM agar or YM broth ATCC® Medium 323: Malt agar medium ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions： | Temperature: 24°C to 26°C Atmosphere: Typical aerobic |
| Sequenced Data： |
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence
GGTTTCCGTAGGTGAACCTGCGGAAGGATCATTACCGAGTGCGGGTCCTTTGGGCCCAACCTCCCATCCGTGTCTATTGTACCCTGTTGCTTCGGCGGGCCCGCCGCTTGTCGGCCGCCGGGGGGGCGCCTCTGCCCCCCGGGCCCGTGCCCGCCGGAGACCCCAACACGAACACTGTCTGAAAGCGTGCAGTCTGAGTTGATTGAATGCAATCAGTTAAAACTTTCAACAATGGATCTCTTGGTTCCGGCATCGATGAAGAACGCAGCGAAATGCGATAACTAATGTGAATTGCAGAATTCAGTGAATCATCGAGTCTTTGAACGCACATTGCGCCCCCTGGTATTCCGGGGGGCATGCCTGTCCGAGCGTCATTGCTGCCCTCAAGCCCGGCTTGTGTGTTGGGTCGCCGTCCCCCTCTCCGGGGGGACGGGCCCGAAAGGCAGCGGCGGCACCGCGTCCGATCCTCGAGCGTATGGGGCTTTGTCACATGCTCTGTAGGATTGGCCGGCGCCTGCCGACGTTTTCCAACCATTCTTTCCAGGTTGACCTCGGATCAGGTAGGGATACCCGCTGAACTTAAGCATATCAATAA D1D2 region of the 28S ribosomal RNA gene ATATCAATAAGCGGAGGAAAAGAAACCAACCGGGATTGCCTCAGTAACGGCGAGTGAAGCGGCAAGAGCTCAAATTTGAAAGCTGGCTCCTTCGGAGTCCGCATTGTAATTTGCAGAGGATGCTTTGGGTGCGGCCCCCGTCTAAGTGCCCTGGAACGGGCCGTCAGAGAGGGTGAGAATCCCGTCTTGGGCGGGGTGTCCGTGCCCGTGTAAAGCTCCTTCGACGAGTCGAGTTGTTTGGGAATGCAGCTCTAAATGGGTGGTAAATTTCATCTAAAGCTAAATACTGGCCGGAGACCGATAGCGCACAAGTAGAGTGATCGAAAGATGAAAAGCACTTTGAAAAGAGAGTTAAACAGCACGTGAAATTGTTGAAAGGGAAGCGCTTGCGACCAGACTCGCCCGCGGGGTTCAGCCGGCATTCGTGCCGGTGTACTTCCCCGTGGGCGGGCCAGCGTCGGTTTGGGCGGCCGGTCAAAGGCCCCTGGAATGTAGTGCCCTCCGGGGCACCTTATAGCCAGGGGTGCAATGCGGCCAGCCTGGACCGAGGAACGCGCTTCGGCACGGACGCTGGCATAATGGTCGTAAACGAC beta-tubulin gene TTGCCCTCCCCGTCCCTCGTCCGTCAGGAGACGCGTCGTTGGTTGGCATCTCTTTTGCTCGGGACCCCACCGGTTCTTCGACCAACTCATTCTTGTGCTAACTGCATGTCTTCTTCGCTTCATAGGTTCACCTCCAAACCGGCCAGTGTGTAAGTGCCAATATATGCTTCGGATGATTGCCCCCAAGGGTCTTGATTGGTGTTTGGTGGACTAAACAATATATCATGGTGGTTAGGGTAACCAAATTGGTGCTGCTTTCTGGTACGTATACAACTGCCATTGGATTGGGGATGGAACATCGTCTCTTAGGCTATCTCAGCTTGAGTTCAGATGTTGTCCATTAGGTACATGCTATCGGTCTAAGAACACGTCTAACAATTCAACAGGCAGACCATCTCTGGCGAGCACGGCCTTGACGGCTCCGGTGTGTAAGTGCAACTTTTTCACACCTCTCAATTGGTCAACAATGGGCAAAGGGTTGGGTCTTCTGACACGCAGGATAGTTACAATGGCACCTCCGACCTCCAGCTGGAGCGCATGAACGTCTACTTCAACGAGGTGAGATCCATCGGACCTTGGCTTTTTCACGACAATATCATCAATGTCCTAATCACTTCAGCAGGCTAGCGGTAACAAGTATGTTCCTCGTGCCGTCCTCGTCGACCTCGAGCCCGGTACCATGGACGCCGTCCGTGCCGGTCCTTTCGGCCAGCTCTTCCGCCCCGACAACTTCGTCTTCGGCCAGTCCGGTGCTGGTAACAACTGG |
| Name of Depositor： | NRRL |
| Chain of Custody： | ATCC <-- NRRL <-- A.J. Moyer strain Doelger 2 |
| References： | Bercovitz A, et al. Localization of pyruvate carboxylase in organic acid-producing Aspergillus strains. Appl. Environ. Microbiol. 56: 1594-1597, 1990. PubMed: 2383004 Schwartz RD. Microbial production of hydroxylated biphenyl compounds. US Patent 4,153,509 dated May 8 1979 Gadsby B, Greenspan G. C-21 hydroxylation products of steroids. US Patent 3,529,000 dated Sep 15 1970 Gibian H, et al. Production of optically active antipodes. US Patent 3,562,112 dated Feb 9 1971 Arfmann HA, Abraham WR. Microbial reduction of aromatic carboxylic acids. Z. Naturforsch. Sect. C Biosci. 48: 52-57, 1993. Auret BJ, Holland HL. Microbiological 18-hydroxylation of steroids. J. Chem. Soc. Commun. 1195: 1157, 1971. Roukas T. Production of citric acid from beet molasses by immobilized cells of Aspergillus niger. J. Food Sci. 56: 878-880, 1991. Drysdale CR, McKay AM. Citric acid production by Aspergillus niger in surface culture on inulin. Lett. Appl. Microbiol. 20: 252-254, 1995. PubMed: 7766122 Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of chromone, chromanone, and ring A hydroxyflavones. J. Nat. Prod. 53: 1471-1478, 1990. PubMed: 2089118 Tran CT, et al. Selection of a strain of Aspergillus for the production of citric acid from pineapple waste in solid-state fermentation. World J. Microbiol. Biotechnol. 14: 399-404, 1998. Heinrich M, Rehm HJ. Formation of gluconic acid at low pH-values by free and immobilized Aspergillus niger during citric acid fermentation. Eur. J. Appl. Microbiol. Biotechnol. 15: 88-92, 1982. Doelger WP, Prescott SC. Citric acid fermentation. Ind. Eng. Chem. 26: 1142-1149, 1934. Betts RE, et al. Microbial transformations of antitumor compounds. I. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602, 1974. PubMed: 4829940 Hang YD, Woodams EE. Apple pomace: a potential substrate for citric acid production by Aspergillus niger. Biotechnol. Lett. 6: 763-764, 1984. Roukas T, Kotzekidon P. Production of citric acid from brewery wastes by surface fermentation using Aspergillus niger. J. Food Sci. 51: 225-228, 1986. Hoffmann JJ, et al. Hydroxygrindelane derivatives by microbial transformation. Phytochemistry 27: 2125-2127, 1988. Arfmann HA, et al. Microbial omega-hydroxylation of trans-nerolidol and structurally related sesquiterpenoids. Biocatalysis 2: 59-67, 1988. Roukas T, Alichanidis E. Citric acid production from beet molasses by cell cycle of Aspergillus niger. J. Ind. Microbiol. 7: 71-74, 1991. Hoffmann JJ, et al. Formation of grindelane dimers by microbial transformation. Phytochemistry 31: 3045-3049, 1992. Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of (+/-)-flavanone and (+/-)-isoflavanone. J. Nat. Prod. 53: 644-656, 1990. PubMed: 2213034 Miura S, et al. Prostaglandin chemistry -- IV. Microbiological kinetic resolution and asymmetric hydrolysis of 3,5-diacetoxycyclopent-1-ene. Tetrahedron 32: 1893-1898, 1976. Kiel H, et al. Citric acid fermentation by Aspergillus niger on low sugar concentrations and cotton waste. Appl. Environ. Microbiol. 42: 1-4, 1981. Martinez-Culebras PV, et al. Molecular characterization of the black Aspergillus isolates responsible for ochratoxin A contamination in grapes and wine in relation to taxonomy of Aspergillus section Nigri. Int. J. Food Microbiol. 132: 33-41, 2009. PubMed: 19401261 |
