| 产品名称： | Aspergillus fumigatus Fresenius |
|---|---|
| 商品货号： | TS203200 |
| Deposited As： | Aspergillus fumigatus Fresenius, anamorph |
| Strain Designations： | NIH 4215 |
| Application： | control with interleukin-12 in rabbits control with BMS 181184 in rabbits control with LY303366 in rabbits control with liposomal nystatin in rabbits Emerging infectious disease research Biomedical Research and Development Material Opportunistic pathogen research Respiratory research |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | frozen |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain： | no |
| Preceptrol®： | no |
| Comments： | control with interleukin-12 in rabbits control with BMS 181184 in rabbits control with LY303366 in rabbits control with liposomal nystatin in rabbits |
| Medium： | ATCC® Medium 28: Emmons modification of Sabourauds agar ATCC® Medium 325: Malt extract agar (Blakeslees formula) ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions： | Temperature: 20°C to 25°C Atmosphere: Typical aerobic |
| Sequenced Data： |
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence TCCGTAGGTGAACCTGCGGAAGGATCATTACCGAGTGAGGGCCCTCTGGGTCCAACCTCCCACCCGTGTCTATCGTACCTTGTTGCTTCGGCGGGCCCGCCGTTTCGACGGCCGCCGGGGAGGCCTTGCGCCCCCGGGCCCGCGCCCGCCGAAGACCCCAACATGAACGCTGTTCTGAAAGTATGCAGTCTGAGTTGATTATCGTAATCAGTTAAAACTTTCAACAACGGATCTCTTGGTTCCGGCATCGATGAAGAACGCAGCGAAATGCGATAAGTAATGTGAATTGCAGAATTCAGTGAATCATCGAGTCTTTGAACGCACATTGCGCCCCCTGGTATTCCGGGGGGCATGCCTGTCCGAGCGTCATTGCTGCCCTCAAGCACGGCTTGTGTGTTGGGCCCCCGTCCCCCTCTCCCGGGGGACGGGCCCGAAAGGCAGCGGCGGCACCGCGTCCGGTCCTCGAGCGTATGGGGCTTTGTCACCTGCTCTGTAGGCCCGGCCGGCGCCAGCCGACACCCAACTTTATTTTTCTAAGGTTGACCTCGGATCAGGTAGGGATACCCGCTGAACTTAAG |
| Name of Depositor： | TJ Walsh |
| Special Collection： | NCRR Contract |
| Isolation： | 19-year-old man with acute lymphoblastic leukemia and neutropenia, Bethesda, MD |
| Cross References： | Nucleotide (GenBank) : KC689330 ITS including 5.8S rRNA gene |
| References： | Roilides E, et al. Interleukin-12 enhances antifungal activity of human mononuclear phagocytes against Aspergillus fumigatus: implications for a gamma interferon-independent pathway. Infect. Immun. 67: 3047-3050, 1999. PubMed: 10338518 Gonzalez CE, et al. Antifungal activity of the pradimicin derivative BMS 181184 in the treatment of experimental pulmonary aspergillosis in persistently neutropenic rabbits. Antimicrob. Agents Chemother. 42: 2399-2404, 1998. PubMed: 9736570 Petraitis V, et al. Antifungal efficacy, safety, and single-dose pharmacokinetics of LY303366, a novel echinocandin B, in experimental pulmonary aspergillosis in persistently neutropenic rabbits. Antimicrob. Agents Chemother. 42: 2898-2905, 1998. PubMed: 9797223 Groll AH, et al. Liposomal nystatin against experimental pulmonary aspergillosis in persistently neutropenic rabbits: efficacy, safety and non-compartmental pharmacokinetics. J. Antimicrob. Chemother. 43: 95-103, 1999. PubMed: 10381106 Thomas J Walsh, personal communication |
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| 产品名称： | Aspergillus fumigatus Fresenius |
|---|---|
| 商品货号： | TS203200 |
| Deposited As： | Aspergillus fumigatus Fresenius, anamorph |
| Strain Designations： | NIH 4215 |
| Application： | control with interleukin-12 in rabbits control with BMS 181184 in rabbits control with LY303366 in rabbits control with liposomal nystatin in rabbits Emerging infectious disease research Biomedical Research and Development Material Opportunistic pathogen research Respiratory research |
| Biosafety Level： | 2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Product Format： | frozen |
| Storage Conditions： | Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section |
| Type Strain： | no |
| Preceptrol®： | no |
| Comments： | control with interleukin-12 in rabbits control with BMS 181184 in rabbits control with LY303366 in rabbits control with liposomal nystatin in rabbits |
| Medium： | ATCC® Medium 28: Emmons modification of Sabourauds agar ATCC® Medium 325: Malt extract agar (Blakeslees formula) ATCC® Medium 336: Potato dextrose agar (PDA) |
| Growth Conditions： | Temperature: 20°C to 25°C Atmosphere: Typical aerobic |
| Sequenced Data： |
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 28S ribosomal RNA gene, partial sequence TCCGTAGGTGAACCTGCGGAAGGATCATTACCGAGTGAGGGCCCTCTGGGTCCAACCTCCCACCCGTGTCTATCGTACCTTGTTGCTTCGGCGGGCCCGCCGTTTCGACGGCCGCCGGGGAGGCCTTGCGCCCCCGGGCCCGCGCCCGCCGAAGACCCCAACATGAACGCTGTTCTGAAAGTATGCAGTCTGAGTTGATTATCGTAATCAGTTAAAACTTTCAACAACGGATCTCTTGGTTCCGGCATCGATGAAGAACGCAGCGAAATGCGATAAGTAATGTGAATTGCAGAATTCAGTGAATCATCGAGTCTTTGAACGCACATTGCGCCCCCTGGTATTCCGGGGGGCATGCCTGTCCGAGCGTCATTGCTGCCCTCAAGCACGGCTTGTGTGTTGGGCCCCCGTCCCCCTCTCCCGGGGGACGGGCCCGAAAGGCAGCGGCGGCACCGCGTCCGGTCCTCGAGCGTATGGGGCTTTGTCACCTGCTCTGTAGGCCCGGCCGGCGCCAGCCGACACCCAACTTTATTTTTCTAAGGTTGACCTCGGATCAGGTAGGGATACCCGCTGAACTTAAG |
| Name of Depositor： | TJ Walsh |
| Special Collection： | NCRR Contract |
| Isolation： | 19-year-old man with acute lymphoblastic leukemia and neutropenia, Bethesda, MD |
| Cross References： | Nucleotide (GenBank) : KC689330 ITS including 5.8S rRNA gene |
| References： | Roilides E, et al. Interleukin-12 enhances antifungal activity of human mononuclear phagocytes against Aspergillus fumigatus: implications for a gamma interferon-independent pathway. Infect. Immun. 67: 3047-3050, 1999. PubMed: 10338518 Gonzalez CE, et al. Antifungal activity of the pradimicin derivative BMS 181184 in the treatment of experimental pulmonary aspergillosis in persistently neutropenic rabbits. Antimicrob. Agents Chemother. 42: 2399-2404, 1998. PubMed: 9736570 Petraitis V, et al. Antifungal efficacy, safety, and single-dose pharmacokinetics of LY303366, a novel echinocandin B, in experimental pulmonary aspergillosis in persistently neutropenic rabbits. Antimicrob. Agents Chemother. 42: 2898-2905, 1998. PubMed: 9797223 Groll AH, et al. Liposomal nystatin against experimental pulmonary aspergillosis in persistently neutropenic rabbits: efficacy, safety and non-compartmental pharmacokinetics. J. Antimicrob. Chemother. 43: 95-103, 1999. PubMed: 10381106 Thomas J Walsh, personal communication |
