| 产品名称： | p43-15 |
|---|---|
| 商品货号： | TS205409 |
| Designations： | p43-15 |
| Species： | Homo sapiens, human |
| Depositors： | LM Kunkel, SA Latt |
| Vector： | Construct size (kb): 8.199999809265137 |
| Insert： | DNA: genomic Insert lengths(kb): 3.799999952316284 Tissue: lymphoblast (49,XXXXY) cell line Gene product: DNA Segment, single copy DXS42 Alleles: A2, A1, C1, C2 |
| Insert Size (kb)： | 3.800 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Comments： | A unique sequence 1.8 kb fragment is generated by PstI/HindIII double digest. Restriction digests of the clone give the following sizes (kb): BamHI--8.2; PstI--5.1, 1.8, 0.7, 0.5; BglII--8.2; HindIII--4.4, 3.7; HindIII/BglII--4.4, 3.5; HindIII/PstI--3.6, 1.6, 1.0, 0.78, 0.5. Linked to the Lowe oculocerebrorenal syndrome (OCRL) (theta = 0, LOD score = 6.63). |
| References： | Aldridge J, et al. A strategy to reveal high-frequency RFLPs along the human X chromosome. Am. J. Hum. Genet. 36: 546-564, 1984. PubMed: 6328976 Wadelius C, et al. Lowe oculocerebrorenal syndrome: DNA-based linkage of the gene to Xq24-q26, using tightly linked flanking markers and the correlation to lens examination in carrier diagnosis. Am. J. Hum. Genet. 44: 241-247, 1989. PubMed: 2912070 Reilly DS, et al. Genetic and physical mapping of Xq24-q26 markers flanking the Lowe oculocerebrorenal syndrome. Genomics 8: 62-70, 1990. PubMed: 2081601 Skare JC, et al. Mapping the X-linked lymphoproliferative syndrome. Proc. Natl. Acad. Sci. USA 84: 2015-2018, 1987. PubMed: 2882515 Reilly DS, et al. Tightly linked flanking markers for the Lowe oculocerebrorenal syndrome, with application to carrier assessment. Am. J. Hum. Genet. 42: 748-755, 1988. PubMed: 2895982 Lesko JG, Nussbaum RL. RFLP locus DXS42 is proximal to the locus for hypoxanthine phosphoribosyltransferase. Am. J. Hum. Genet. 39: 669-670, 1986. PubMed: 2878611 Louis M Kunkel, personal communication |
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| 产品名称： | p43-15 |
|---|---|
| 商品货号： | TS205409 |
| Designations： | p43-15 |
| Species： | Homo sapiens, human |
| Depositors： | LM Kunkel, SA Latt |
| Vector： | Construct size (kb): 8.199999809265137 |
| Insert： | DNA: genomic Insert lengths(kb): 3.799999952316284 Tissue: lymphoblast (49,XXXXY) cell line Gene product: DNA Segment, single copy DXS42 Alleles: A2, A1, C1, C2 |
| Insert Size (kb)： | 3.800 |
| Media： | ATCC® Medium 1227: LB Medium (ATCC medium 1065) with 50 mcg/ml ampicillin |
| Biosafety Level： | 1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Comments： | A unique sequence 1.8 kb fragment is generated by PstI/HindIII double digest. Restriction digests of the clone give the following sizes (kb): BamHI--8.2; PstI--5.1, 1.8, 0.7, 0.5; BglII--8.2; HindIII--4.4, 3.7; HindIII/BglII--4.4, 3.5; HindIII/PstI--3.6, 1.6, 1.0, 0.78, 0.5. Linked to the Lowe oculocerebrorenal syndrome (OCRL) (theta = 0, LOD score = 6.63). |
| References： | Aldridge J, et al. A strategy to reveal high-frequency RFLPs along the human X chromosome. Am. J. Hum. Genet. 36: 546-564, 1984. PubMed: 6328976 Wadelius C, et al. Lowe oculocerebrorenal syndrome: DNA-based linkage of the gene to Xq24-q26, using tightly linked flanking markers and the correlation to lens examination in carrier diagnosis. Am. J. Hum. Genet. 44: 241-247, 1989. PubMed: 2912070 Reilly DS, et al. Genetic and physical mapping of Xq24-q26 markers flanking the Lowe oculocerebrorenal syndrome. Genomics 8: 62-70, 1990. PubMed: 2081601 Skare JC, et al. Mapping the X-linked lymphoproliferative syndrome. Proc. Natl. Acad. Sci. USA 84: 2015-2018, 1987. PubMed: 2882515 Reilly DS, et al. Tightly linked flanking markers for the Lowe oculocerebrorenal syndrome, with application to carrier assessment. Am. J. Hum. Genet. 42: 748-755, 1988. PubMed: 2895982 Lesko JG, Nussbaum RL. RFLP locus DXS42 is proximal to the locus for hypoxanthine phosphoribosyltransferase. Am. J. Hum. Genet. 39: 669-670, 1986. PubMed: 2878611 Louis M Kunkel, personal communication |
